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Bone Resorption Test

 

Why Test Bone Resorption?

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Bone resorption is a process by which bone is degraded and leads to the release of calcium and proteins from the bone structure into the blood where it is filtered by the kidneys and detected in urine. During growth and development, bone synthesis occurs at a faster rate than bone resorption.

However as people age, the rate of bone growth slows, and bone resorption occurs faster than new bone growth. When this occurs, bone density decreases, which may lead to osteoporosis and injury as a result of falls. Low bone density is the leading cause of persons seeking assisted living.

High levels of NTx (cross linked N-teleopeptides of type I collagen) can be a sign of osteoporosis, while low levels may indicate over-treatment of osteoporosis with bisphosphonates.